The dominant Western culture has created a legal system premised upon an individualistic and commercial foundation for intellectual property rights (IPR). This system necessarily excludes the protection of traditional knowledge and other components of Indigenous cultures, as well as concepts of communal responsibility for the keeping and transfer of such ideas and knowledge. These concepts are foundational to Indigenous knowledge systems in Alaska, as well as throughout the world. Today, a focus on this issue is critical to the preservation of indigenous cultures and their ways of knowing. We examine where national and international intellectual property rights systems are in addressing Indigenous cultural and intellectual property rights (Indigenous CIPR). We also examine opportunities for expansion of such rights in Alaska and around the world.