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    Health benefits of the hunter/gatherer lifestyle

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    Author
    Coker, Melynda Sheri
    Chair
    Greenberg, Joshua
    Committee
    Brinkman, Todd
    Duffy, Lawrence
    Lindberg, Mark
    Keyword
    Hunting and gathering societies
    Health
    Hygiene
    Nutrition
    Subsistence hunting
    Metabolism
    Amino acids
    Proteins in human nutrition
    Wildlife as food
    Beef
    Reindeer
    Muscle proteins
    Blood lipoproteins
    Lipids
    Proteins
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    URI
    http://hdl.handle.net/11122/12604
    Abstract
    The Hunter/Gatherer Lifestyle has long been associated with positive health benefits. I measured specific metabolic parameters associated with this lifestyle, highlighting lean tissue preservation. Severe loss of lean tissue mass (LTM) (sarcopenia) is a progressive, multifactorial disease presenting with decreased functional performance, age-related bone loss, increased falls and fractures, obesity, type II diabetes mellitus, depression, hospitalization, and even mortality. Degradation of LTM, often accompanied with obesity, is cost-prohibitive emotionally, physically, and financially. To counteract LTM deterioration, a positive net protein balance (NB) must be created through increased protein synthesis or suppressed protein breakdown. I utilized isotope tracer infusion methodology to compare equivalent serving sizes of wild, freerange red meat (FR) to grain-fed commercial meat (CB) on human NB. I observed that FR elicited significantly higher NB than CB due to greater suppression of protein breakdown. I next asked if an unscripted 8-12-day Alaska expeditionary backcountry hunt (ABEH) for moose, caribou, and sheep hunters would be executed in negative energy balance and positively influence metabolic markers while maintaining LTM. I found that energy expenditure was far greater than intake and contributed to reductions in body weight, adipose tissue, serum lipids, and intrahepatic lipid, while preserving LTM. Finally, I asked if a proprietary drink with a unique amino acid formulation (EMR) similar to FR could elicit fat loss and LTM maintenance in a cohort unlikely to gain access to FR. EMR or Optifast® was provided once per day to obese, elderly individuals. With no additional manipulations and in one month, there was a net gain of thigh muscle cross-sectional area and significant reductions in total and visceral fat mass. Concluding, I sought specific metabolic outcomes derived from distinct aspects of the understudied hunter/gatherer lifestyle (i.e., FR, ABEH, EMR). I found positive influences on health which would contribute to LTM preservation during aging, decreasing individual, family, and societal burdens linked to loss of LTM. These findings provide increased emotional, physical, and financial value to the hunter/gatherer lifestyle.
    Description
    Thesis (Ph.D.) University of Alaska Fairbanks, 2021
    Table of Contents
    Chapter 1. General Introduction -- 1.2. Background -- 1.2. Introduction to chapter two: equivalent servings of free-range reindeer promote higher net protein balance compared to commercial beef -- 1.3. Introduction to chapter three: Alaska backcountry expeditionary hunting promotes rapidimprovements in metabolic biomarker in healthy males and females -- 1.4. Introduction to chapter four: once/day provision of essential amino acid enriched mealreplacement improves body composition and physical function in obese elderly: a randomized controlled trial -- 1.5. Closing introductory statement -- References. Chapter 2. Equivalent servings of free-range reindeer promote greater net proteinbalance compared to commercial beef -- 2.1. Abstract -- 2.2. Introduction -- 2.3. Materials and methods -- 2.3.1. Analytical methods -- 2.3.2. Statistical methods -- 2.4. Results -- 2.5. Discussion -- 2.6. Conclusion -- 2.7. Acknowledgments -- 2.8. Conflicts of interest -- 2.9. Author contributions -- 2.10. Sources of support -- 2.11. References. Chapter 3. Alaska backcountry expeditionary hunting promotes rapid improvements in metabolic biomarkers in healthy males and females -- 3.1. Abstract -- 3.2. Introduction -- 3.3. Methods -- 3.3.1. Alaska backcountry hunting immersion -- 3.3.2. Imaging measurements -- 3.3.3. Isotopic methodology -- 3.3.4. Dietary intake -- 3.3.5. Statistical analysis -- 3.4. Results -- 3.4.1. ABEH overview -- 3.4.2. Total energy expenditure -- 3.4.3. Total energy intake -- 3.4.4. Macronutrient intake -- 3.4.5. Body weight and body composition -- 3.4.6. Intrahepatic lipid -- 3.4.7. Blood/serum parameters -- 3.5. Discussion -- 3.6. Conclusion -- 3.7. Acknowledgments -- 3.8. Conflicts of interest -- 3.9. Author contributions -- 3.10. Sources of support -- 3.11. References. Chapter 4. Once/day provision of essential amino acid enriched meal replacement improves body composition and physical function in obese elderly -- 4.1. Abstract -- 4.2. Introduction -- 4.3. Methods -- 4.3.1. Recruitment -- 4.3.2. Exclusion criteria -- 4.3.3. Study participants -- 4.3.4. Body composition -- 4.4.3. Skeletal muscle -- 4.4.4. Liver lipid -- 4.4.5. Physical function -- 4.4.6. Blood parameters -- 4.5. Discussion -- 4.6. Conclusions -- 4.7. Acknowledgments -- 4.8. Conflicts of interest -- 4.9. Author contributions -- 4.10. Sources of support -- 4.11. References. Chapter 5. Summary and conclusions -- 5.1. Discussion -- 5.2. Future directions -- 5.3. Conclusions -- 5.4. References. Appendix.
    Date
    2021-08
    Type
    Thesis
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    New theses and dissertations

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