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    Mitochondrial succinate dehydrogenase enzyme activity in hibernating black bears

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    Brennan_RCA 2025.pdf
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    Description:
    Research Poster
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    Author
    Brennan, Madelyn
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    URI
    http://hdl.handle.net/11122/15903
    Description
    Mentor: Dr. Sarah Rice; Black bears suppress their metabolism by 75% in hibernation and 50% during spring emergence, but the mechanisms regulating metabolic suppression are unknown. Studies in hibernating ground squirrels have suggested that inhibition of mitochondrial succinate dehydrogenase activity (SDH, complex II) could play a role in metabolic suppression. SDH activity has not been measured in hibernating black bears before. We hypothesized that SDH activity would be lower during hibernation and spring emergence compared to summer levels in kidney, cardiac, skeletal muscle, and liver tissue of black bears.
    Date
    2025-04-01
    Type
    Poster
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    2025 Research and Creative Activity Day Posters

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