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    Tribological Comparison of Materials

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    Shi_Bing_12-2004.pdf
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    Author
    Shi, Bing
    Chair
    Duffy, Lawrence K.
    Committee
    Kuhn, Thomas B.
    Liang, Hong
    Rekow, Dianne
    Metadata
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    URI
    http://hdl.handle.net/11122/4798
    Abstract
    Approximately 600,000 total joint replacement surgeries are performed each year in the United States. Current artificial joint implants are mainly metal-on-plastic. The synthetic biomaterials undergo degradation through fatigue and corrosive wear from load-bearing and the aqueous ionic environment of the human body. Deposits o f inorganic salts can scratch weight-bearing surfaces, making artificial joints stiff and awkward. The excessive wear debris from polyethylene leads to osteolysis and potential loosening of the prosthesis. The lifetime for well-designed artificial joints is at most 10 to 15 years. A patient can usually have two total joint replacements during her/his lifetime. Durability is limited by the body’s reaction to wear debris of the artificial joints. Wear of the artificial joints should be reduced. A focus of this thesis is the tribological performance of bearing materials for Total Replacement Artificial Joints (TRAJ). An additional focus is the scaffolds for cell growth from both a tissue engineering and tribological perspective. The tribological properties of materials including Diam ond-like Carbon (DLC) coated materials were tested for TRAJ implants. The DLC coatings are chemically inert, impervious to acid and saline media, and are mechanically hard. Carbon-based materials are highly biocompatible. A new alternative to total joints implantation is tissue engineering. Tissue engineering is the replacement of living tissue with tissue that is designed and constructed to meet the needs of the individual patient. Cells were cultured onto the artificial materials, including metals, ceramics, and polymers, and the frictional properties of these materials were investigated to develop a synthetic alternative to orthopedic transplants. Results showed that DLC coated materials had low friction and wear, which are desirable tribological properties for artificial joint material. Cells grew on some of the artificial matrix materials, depending on the surface chemistry, wettability, morphology, microstructure etc. The dry, lubricated, and cell culture friction tests showed that bovine serum albumin solution and culture media performed as lubricants. Frictional properties varied. Glass and TR-2 (PET, polyethylene terephthalate) showed good cell culture results and low friction. Both are suitable materials, both as artificial joint implant coatings and as substrates for preparing total joint implants via tissue engineering.
    Description
    Dissertation (Ph.D.) University of Alaska Fairbanks, 2004
    Table of Contents
    Signature Page -- Title page -- Abstract -- Table of Contents -- List of Figures -- List of Tables xiii List of Appendices -- Acknowledgements -- Chapter 1: Introduction -- Chapter 2: Experimental: materials, equipment, and methods -- Chapter 3: Tribological performance of alternative bearing materials for TRAJ: results and discussion -- Chapter 3: Tribological performance of materials as scaffolds for cell growth: Results and discussion of cell culture - a tissue engineering approach -- Chapter 4: Tribological performance of materials as scaffolds for cell growth: Results and discussion of cell culture - a tissue engineering approach -- Chapter 5: Tribological performance of materials as scaffolds for cell growth: Results and discussion of tribological tests -- Chapter 6: Conclusions and future work -- Reference -- Appendices
    Date
    2004-12
    Type
    Dissertation
    Collections
    Chemistry and Biochemistry

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